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summary Macrophage migration inhibitory aspect (MIF) can be a proinflammatory cytokine encoded inside a functionally polymorphic genetic locus. MIF was originally identified like a cytokine generated by activated T cells, but in the latest days it's been discovered for a multipotent essential cytokine secreted by all kinds of other cell forms invol
We further confirmed that CPSI-1306, a small-molecule MIF inhibitor, inhibits The expansion of TNBC cells in vitro. Mechanistic scientific studies disclosed that CPSI-1306 induces intrinsic apoptosis by alteration in mitochondrial membrane possible, cytochrome c (Cyt c) release, and activation of different caspases. Furthermore, CPSI-1306 inhibits
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